Sugar comes from either sugar cane or sugar beets while high fructose corn syrups come from corn. Table sugar and the HFCS used in soft drinks have the same calories and sweetness and research shows that our bodies cannot differentiate one from the other. Both table sugar and HFCS are made up of the two simple sugars, fructose and glucose. The difference between the two sweeteners is in the amount of these two simple sugars they contain. Specifically, table sugar is made of 50% fructose and 50% glucose while the most common type of HFCS is made of 55% fructose and 45% glucose.